Peptides and compounds that bind to a receptor

Details Peptides and compounds that bind to a receptor Peptides and compounds that bind to a receptor

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) A61K 38/19 (2006.01) A61P 7/00 (2006.01) C07K 17/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2274149

Described are peptides and compounds that bind to and activate the thrombopoietin receptor. Such peptides and compounds are useful in methods for treating haematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labelled peptides and compounds.

L'invention a pour objet des peptides et des composés qui se lient au récepteur de thrombopoïétine et activent ce dernier. Ces peptides et ces composés sont utiles pour traiter les troubles hématologiques et, en particulier, la thrombocytopénie provoquée par la chimiothérapie, la thérapie par rayonnement ou les transfusions de moelle osseuse . Ils présentent également une grande utilité dans des techniques de diagnostic utilisant des peptides et des composés marqués.

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