Peptides and compounds that bind to a thrombopoietin receptor

Details Peptides and compounds that bind to a thrombopoietin receptor Peptides and compounds that bind to a thrombopoietin receptor

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) C07K 7/06 (2006.01) C07K 14/00 (2006.01) C07K 14/52 (2006.01) C07K 17/08 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2636432

Receptor are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.

Les récepteurs sont des peptides et des peptides mimétiques se liant au récepteur de la thrombopoïétine et activant ce dernier. Ces peptides et ces peptides mimétiques sont utiles dans des méthodes visant le traitement d'affections hématologiques et, en particulier, la thrombocytopénie résultant de la chimiothérapie, la radiothérapie ou les transfusions de moelle osseuse, et les méthodes diagnostiques faisant appel à des peptides et des peptides mimétiques marqués.

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