Peptides and compounds that bind to the il-5 receptor

Details Peptides and compounds that bind to the il-5 receptor Peptides and compounds that bind to the il-5 receptor

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/20 (2006.01) C07K 14/715 (2006.01) C12N 15/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2294519

Described are peptides and peptide mimetics that bind to the IL-5 receptor. Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response to IL-5 and or the production and accumulation of eosinophils, such as asthma, as well as in diagnostic methods employing labeled peptides and peptide mimetics.

L'invention concerne des peptides et des mimétiques des peptides qui se lient au récepteur de l'interleukine 5. Ces peptides et ces mimétiques des peptides sont utiles pour traiter des troubles, tels que l'asthme, qui impliquent une mauvaise production de l'interleukine 5 ou une mauvaise réponse à l'interleukine 5 ainsi qu'une accumulation d'éosinophiles. Ces peptides et ces mimétiques présentent également une grande utilité dans des procédés de diagnostique utilisant des peptides marqués et des mimétiques de peptides.

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