C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2713423
Host RNA/viral protein interaction as a target of intervention in the replication of viruses, e.g., the human immunodeficiency virus (HIV) are described. The target being upstream of the final replication product, and being crucial to the viral replication, is less likely to be genetically altered to drug resistance. Peptides that intervene in this RNA/viral protein interaction are also described, as well as compositions containing the same and methods of use thereof.
L'invention concerne l'interaction ARN hôte/protéine virale dans la réplication de virus, par exemple le virus de l'immunodéficience humaine (VIH). La cible de l'invention se produit en amont du produit de réplication final et, étant cruciale pour la réplication virale, elle est moins susceptible d'être génétiquement modifiée pour résister aux médicaments. L'invention concerne également les peptides intervenant dans cette interaction ARN/protéine virale, ainsi que des compositions contenant ceux-ci et des méthodes d'utilisation de ceux-ci.
North Carolina State University
Robic
LandOfFree
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