A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/21 (2006.01) A61K 31/56 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/64 (2006.01) C07K 14/82 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2232750
The present invention provides peptides, cyclized peptides and peptidomimetics which inhibit the oncogenic and/or transforming activity of the p21 <u>ras</u> protein, pharmaceutical compositions containing at least one of the <u>ras</u>- inhibiting peptides, cyclized peptides and peptidomimetics, and methods for inhibiting the <u>ras</u>-mediated oncogenic and/or transformation process in mammalian cells or tissues.
L'invention porte sur des peptides, peptides cyclisés et mimes de peptides inhibiteurs de l'action oncogénique et/ou transformatrice de la protéine p21 <u>ras</u>, sur des préparations pharmaceutiques contenant au moins l'un des peptides, peptides cyclisés et mimes de peptides, inhibiteurs de la protéine p21 <u>ras</u>, et sur des procédés d'inhibition des processus oncogénique et/ou de transformation induits par la protéine p21 <u>ras</u> dans des cellules ou tissus de mammifères.
Abajian Henry Baxter
Hlavka Joseph J.
Kende Andrew S.
Noble John Fowler
Pincus Matthew R.
Innapharma Inc.
Mckay-Carey & Company
Tetragenex Pharmaceuticals Inc.
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