Peptides and peptidomimetics with structural similarity to...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 14/82 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01) C07K 7/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2213229

The present invention provides peptides and peptidomimetics corresponding to part or to the entirety of the region encompassed by residues 360-386 of human p53, said peptides and peptidomimetics characterized by the ability to activate DNA binding of wild-type p53 and to select tumor-derived p53 mutants. Pharmaceutical compositions of the compounds of the invention and methods of using these compositions therapeutically are also provided.

La présente invention décrit des peptides et des molécules à comportement mimétique des peptides correspondant à tout ou partie de la région entourée de résidus 360-386 de la protéine p53 humaine, lesdits peptides et molécules à comportement mimétique des peptides étant caractérisés par la capacité d'activer la liaison de l'ADN de la protéine p53 de type sauvage et de sélectionner les mutants de la protéine p53 tirés de tumeurs. L'invention décrit également des compositions pharmaceutiques faites des composés de l'invention et des procédés pour utiliser ces compositions à des fins thérapeutiques.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Peptides and peptidomimetics with structural similarity to... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides and peptidomimetics with structural similarity to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides and peptidomimetics with structural similarity to... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2016112

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.