Peptides associated with hla-dr mhc class ii molecule and...

Details Peptides associated with hla-dr mhc class ii molecule and... Peptides associated with hla-dr mhc class ii molecule and...

C - Chemistry, Metallurgy

07

K

C07K 14/75 (2006.01) A61K 38/17 (2006.01) A61P 19/02 (2006.01) C07K 1/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) G01N 33/564 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2421321

Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with Rheumatoid Arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of Rheumatoid Arthritis.

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