A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 38/12 (2006.01) A61K 47/48 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/44 (2006.01)
Patent
CA 2491310
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
L'invention présente des découvertes surprenantes concernant le rôle de phospholipides et d'aminophospholipides anioniques dans le système vasculaire tumoral et dans le commencement et le développement viral, ainsi que des compositions et des procédés d'utilisation de ces découvertes dans le traitement du cancer et d'infections virales. L'invention concerne également des compositions à base d'anticorps, d'immunoconjugués et de duramycine avantageuses ainsi que des combinaisons se fixant à et inhibant des phosphospholipides et des aminophospholipides anioniques, destinées à être utilisées dans le traitement sans danger et efficace du cancer, d'infections virales et de maladies apparentées.
He Jin
Huang Xianming
Ran Sophia
Soares Melina M.
Thorpe Philip E.
Board Of Regents The University Of Texas System
R. William Wray & Associates
LandOfFree
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