Peptides capable of inhibiting the endocytosis of the app...

Details Peptides capable of inhibiting the endocytosis of the app... Peptides capable of inhibiting the endocytosis of the app...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2268018

The invention concerns novel peptide and nucleotide sequences, and their pharmaceutical use. More particularly, it concerns novel peptides capable of inhibiting at least partially the phenomenon of APP endocytosis by intervening at the level of the interaction of the FE65 protein with the cytoplasmic region of the APP.

La présente invention concerne de nouvelles séquences peptidiques et nucléotidiques, et leur utilisation pharmaceutique. Plus particulièrement, la présente invention concerne de nouveaux peptides capable d'inhiber au moins partiellement le phénomène d'endocytose de l'APP en interférant au niveau de l'interaction de la protéein FE65 avec la région cytoplasmique de l'APP.

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