C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2559215
The invention relates to a peptide that is a maturation product of the Basic Prolin-rich Lacrinal Protein (BPLP) or a peptide derivative or a mimetic of said maturation product, wherein the peptide or peptide derivative or mimetic exhibits an inhibitory property against a metallo-ectopeptidase, especially NEP and/or APN. The present invention also relates to polynucleotides coding for said peptides and to antibodies directed against said peptides. Furthermore, the present invention relates to diagnostic and therapeutic uses of human BPLP protein and inhibitory peptides derived therefrom, polypeptides coding for human BPLP protein or peptides derived therefrom as well as antibodies directed against BPLP protein or peptides derived therefrom.
L'invention concerne un peptide qui est un produit de maturation de la protéine lacrinale riche en proline de base (BPLP) ou un dérivé du peptide ou un élément mimétique du produit de maturation, le peptide ou le dérivé du peptide ou l'élément mimétique possédant une propriété inhibitrice contre une métallo-ectopeptidase, notamment NEP et/ou APN. L'invention concerne également des polynucléotides codant les peptides et des anticorps dirigés contre les peptides. De plus, l'invention concerne des utilisations diagnostiques et thérapeutiques de la protéine BPLP humaine et des peptides inhibiteurs dérivés de celle-ci, des polypeptides codant la protéine BPLP humaine ou des peptides dérivés de celle-ci, ainsi que des anticorps dirigés contre la protéine BPLP ou des peptides dérivés de celle-ci.
Dufour Evelyne
Huaulme Jean-Francois
Rougeot Catherine
Ungeheuer Marie-Noelle
Wisner Anne
Institut Pasteur
Robic
LandOfFree
Peptides derived from human bplp protein, polynucleotides... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptides derived from human bplp protein, polynucleotides..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides derived from human bplp protein, polynucleotides... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1695232