Peptides derived from plasminogen activator inhibitor-1 and...

Details Peptides derived from plasminogen activator inhibitor-1 and... Peptides derived from plasminogen activator inhibitor-1 and...

A - Human Necessities

61

K

A61K 38/08 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2694214

The present invention relates to isolated 18-mer peptides corresponding to amino acid residues 369-386 of human plasminogen activator inhibitor 1(PAI-1) and fragments thereof, compositions comprising same, and uses thereof for treating throm-boembolic diseases and pathological conditions associated with neurological damage.

La présente invention porte sur des peptides 18-mers isolés correspondant aux résidus d'acides aminés 369-386 de l'inhibiteur 1 de l'activateur du plasminogène (PAI-1) et à des fragments de celui-ci, sur des compositions les comprenant, et sur des utilisations de ceux-ci pour traiter des maladies thromboemboliques et des états pathologiques associés à un dommage neurologique.

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