Peptides enhancing ceh activity or inhibiting acat activity,...

Details Peptides enhancing ceh activity or inhibiting acat activity,... Peptides enhancing ceh activity or inhibiting acat activity,...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2531890

Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.

L'invention concerne des peptides et des mimétiques de domaines choisis de l'isoforme 2.1 de l'amyloïde sérique (SAA2.1) de mammifère. L'invention concerne également des composés et des compositions renforçant l'activité de la cholestérol-ester-hydrolase sur des macrophages et/ou inhibant l'activité de la cholestérol-acyl-transférase CoA. L'invention concerne encore des méthodes d'utilisation de ces compositions dans le traitement et/ou la prévention de l'athérosclérose, de la coronaropathie et des maladies cardio-vasculaires.

Affiliated with

Also associated with

Rating

Peptides enhancing ceh activity or inhibiting acat activity,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides enhancing ceh activity or inhibiting acat activity,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides enhancing ceh activity or inhibiting acat activity,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1464612