Peptides for circulatory system control

Details Peptides for circulatory system control Peptides for circulatory system control

C - Chemistry, Metallurgy

07

K

530/7.1, 167/103

C07K 14/58 (2006.01) A61K 38/12 (2006.01) A61K 38/22 (2006.01) C07K 7/56 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339997

Peptides represented by the formula: H-(A)m-Y-Phe-Z-Gly-Arg-X-Asp-Arg-Ile-Gly-Ala-Gln-Ser- Gly-Leu-Gly-Y-(B)n-OH wherein X represents Met, Met(O), Nle, or Ile; Y represents a cystine residue or an .alpha.-amino suberic acid residue; Z represents Gly or Ala; m and n each represent 0 or 1; A represents Ser, Ser-Ser, Arg-Ser-Ser, Arg-Arg-Ser-Ser, Leu-Arg- Arg-Ser-Ser, or Ser-Leu-Arg-Arg-Ser-Ser; and B represents Asn, Asn-Ser, Asn-Ser-Phe, Asn-Ser-Phe- Arg, or Asn-Ser-Phe-Arg-Tyr; with the proviso that .alpha.-hANP(1-28), .alpha.-rANP(1-28), .alpha.-rANP(4-28), .alpha.-rANP(5- 27), .alpha.-rANP(5-25) and .alpha.-rANP(3-28) are excluded from the compounds represented by the formula; are disclosed along with methods of using these compounds. These peptides are useful as drugs such as diuretic agents, therapeutic agents for hypertension and heart diseases and as muscle relaxing agents.

489535

Affiliated with

Also associated with

Rating

Peptides for circulatory system control does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides for circulatory system control, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides for circulatory system control will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1191254