Peptides for inducing cytotoxic t lymphocyte responses to...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/36 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 39/29 (2006.01) A61K 39/385 (2006.01) A61P 31/20 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/02 (2006.01)

Patent

CA 2594184

Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV envelope, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.

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