C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/43 (2006.01)
Patent
CA 2571350
The invention relates to a nucleic acid sequence that codes for peptides which inhibit the interaction of protein kinase A (PKA) and protein kinase A-anchor proteins (AKAP), a host organism, which has the nucleic acid sequence and, optionally, expresses the peptides. The invention also relates to the use of the peptides and of the host organism when studying diseases, which are associated with the AKAP PKA interaction, and to the use of the peptides as a pharmaceutical agent for treating diseases of this type.
La présente invention concerne une séquence d'acide nucléique codant pour des peptides qui inhibent l'interaction de la protéine kinase A (PKA) et des protéines d'ancrage de la protéine kinase A (AKAP), un organisme hôte qui comporte la séquence d'acide nucléique et éventuellement exprime ces peptides, ainsi que l'utilisation desdits peptides et de l'organisme hôte pour l'étude de maladies qui sont associées à l'interaction AKAP - PKA et l'utilisation desdits peptides en tant que principe pharmaceutique pour le traitement de maladies de ce type.
Hundsrucker Christian
Klussmann Enno
Rosenthal Walter
Deeth Williams Wall Llp
Forschungsverbund Berlin E. V.
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