C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/7.26
C07K 14/655 (2006.01)
Patent
CA 1129846
X-4758 -1- Abstract of the Disclosure The tetradecapeptides of the formula Image (III) wherein X is H-Ala-D-Ala, H-D-Ala-Gly, or H-D-Val-Gly; and X1 is Ala-Leu, Ala-Phe, Ala-D-Phe, D-Ala-Phe, or D-Ala-Cha; or the non-toxic, pharmaceutically acceptable acid addition salts thereof; inhibit secretion of growth hormone, while not materially inhibiting the secretion of insulin or glucagon. Intermediates used in the synthesis of the tetradecapeptides are also described.
336401
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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