Peptides that induce t cell responses

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2327549

Peptides from cancer related protein products of frameshift mutated genes which eliciting T cellular immunity for use in cancer vaccines and compositions for anticancer treatment.

L'invention concerne l'utilisation d'analogues d'acides gras non bêta-oxydables, de formule générale (I) : alkyl-X-CH2COOR, dans laquelle alkyle représente un groupe hydrocarboné saturé ou insaturé présentant 8 à 22 atomes de carbone, X représente O, S, SO, SO2, et Se, et R représente hydrogène ou alkyle C1-C4. Ces analogues sont notamment utiles à la préparation d'une composition pharmaceutique permettant de traiter et/ou de prévenir les états liés au syndrome X, à l'exception de ceux revendiqués dans la demande de brevet européen 345.038, et dans la demande de brevet international WO97/003663. L'invention concerne également une méthode de traitement et/ou de prévention de ces états liés au syndrome X.

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