C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/16 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61P 31/12 (2006.01) C07K 14/475 (2006.01) C07K 14/515 (2006.01) C07K 14/52 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2387604
The invention relates to a peptide of formula (I): (A)¿n? - A1-A2 - A1 - A3 - A4 - A1 - (A)¿m?, wherein A is any amino acid, n and m are each whole numbers from 0 to 20, the sum of which n + m is between 0 and 20, preferably between 0 and 15 and especially preferably between 0 and 10, A1 is a basic amino acid, especially lysine (Lys) or arginine (Arg), A2 is an amino acid selected from the following: basic amino acids, glutamic acid (Glu), glycine (Gly), aspartic acid (Asp); A3 is an amino acid selected from the following: basic amino acids, proline (Pro), glutamic acid (Glu), glutamine (Gln); and A4 is an amino acid selected from the following: basic amino acids, glutamic acid (Glu), glycine (Gly), serine (Ser), valine (Val).
La présente invention se rapporte à un peptide répondant à la formule (I): (A)n - A1A1 - A2 - A1 - A3 - A4 - A1 - (A)m dans laquelle : A est un acide aminé quelconque, n et m sont chacun des nombres entiers de 0 à 20 dont la somme n + m est comprise entre 0 et 20, de préférence entre 0 et 15 et tout préférentiellement entre 0 et 10, A1 est un acide aminé basique et plus particulièrement la lysine (Lys) ou l'arginine (Arg), A2 est un acide aminé choisi parmi : les acides aminés basiques, l'acide glutamique (Glu), la glycine (Gly), l'acide aspartique (Asp), A3 est un acide aminé choisi parmi : les acides aminés basiques, la proline (Pro), l'acide glutamique (Glu), la glutamine (Gln), A4 est un acide aminé choisi parmi : les acides aminés basiques, l'acide glutamique (Glu), la glycine (Gly), la sérine (Ser), la valine (Val).
Achour Ammar
Barritault Denis
Courty Jose
Centre National de La Recherche Scientifique (cnrs)
Gowling Lafleur Henderson Llp
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