Peptides with capacity to bind to scurfin and applications

Details Peptides with capacity to bind to scurfin and applications Peptides with capacity to bind to scurfin and applications

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2706201

The invention relates to peptides of general formula (I), wherein X is absent or X is present and is X14 or X14-X15, wherein X14 and X15 independently from one another, represent an amino acid; their functional variants and fragments, and their pharmaceutically acceptable salts, having the capacity to bind to scurfin and inhibit its biological activity, therefore they regulate or block the activity of regulatory T (Treg) lymphocytes. They are applicable in the treatment of infectious and neoplastic diseases. Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-X (I)

L'invention concerne des peptides de formule générale (I), dans laquelle X est absent, ou bien X est présent et représente X14 ou X14-X15, X14 et X15 représentant indépendamment l'un de l'autre un acide aminé; leurs variants et fragments fonctionnels, et leurs sels acceptables sur le plan pharmaceutique. Lesdits peptides présentent la capacité de pouvoir se lier à la scurfine et celle d'inhiber l'activité biologique de cette dernière, ce qui leur permet de pouvoir réguler ou de bloquer l'activité des lymphocytes T régulateurs (Treg). Lesdits peptides peuvent être utilisés dans le traitement de maladies infectieuses et néoplasiques

Affiliated with

Also associated with

Rating

Peptides with capacity to bind to scurfin and applications does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides with capacity to bind to scurfin and applications, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides with capacity to bind to scurfin and applications will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1912695