C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/575 (2006.01) A61K 38/22 (2006.01) C07K 7/08 (2006.01)
Patent
CA 2594423
The present invention refers to neuropeptide-2 receptor agonists of the formula (I): Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-NH2 (I); as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical composition's containing them, are useful for the treatment of diseases such as, for example, obesity.
L'invention porte sur un agoniste du récepteur du neuropeptide-2, de formule (I): Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-NH2 (I); sur ses sels, dérivés et fragments pharmacocompatibles, et dont les substituts sont tels que décrits dans la spécification. Ces composés et les préparations pharmaceutiques les contenant s'avèrent utiles pour le traitement de maladies telles que par exemple l'obésité.
Danho Waleed
Ehrlich George
Fry David C.
Khan Wajiha
Swistok Joseph
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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