C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01)
Patent
CA 2737922
The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides.
La présente invention concerne des polypeptides réticulés biologiquement actifs ayant des propriétés améliorées par rapport à leurs polypeptides précurseurs correspondants, ayant de bonnes propriétés de pénétration cellulaire et une liaison réduite à des protéines humaines. Linvention concerne en outre des procédés didentification et de préparation de tels polypeptides améliorés.
Annis David Allen
Kapeller-Libermann Rosana
Kawahata Noriyuki
Nash Huw M.
Sawyer Tomi K.
Aileron Therapeutics Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Peptidomimetic macrocycles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptidomimetic macrocycles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptidomimetic macrocycles will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1839041