Peptidomimetic macrocycles with improved properties

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 2/00 (2006.01) A61K 38/00 (2006.01) C07K 1/107 (2006.01)

Patent

CA 2743177

The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.

La présente invention concerne des macrocycles peptidomimétiques biologiquement actifs présentant des propriétés améliorées en ce qui concerne leurs polypeptides correspondants. Linvention concerne en outre des procédés de préparation et dutilisation de tels macrocycles, par exemple dans des applications thérapeutiques.

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