C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/605 (2006.01) A61K 38/26 (2006.01)
Patent
CA 2707448
The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-I receptor agonistic activity.
La présente invention porte sur de nouveaux peptidomimétiques de formule (I) qui agissent principalement en tant que secrétagogues de l'insuline dépendants du glucose. En plus de leur activité agoniste des récepteurs de GLP-1, ces peptidomimétiques présentent une activité antagoniste des récepteurs de glucagon.
Bahekar Rajesh H.
Jain Mukul R.
Patel Pankaj Ramanbhai
Cadila Healthcare Limited
Kirby Eades Gale Baker
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