Peptidyl compounds and their therapeutic use

Details Peptidyl compounds and their therapeutic use Peptidyl compounds and their therapeutic use

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/415 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2219973

Peptidyl derivatives having an SH or acylo groups and which are amides, primary amides or thioamides, have therapeutic utility via MMP or TNF inhibition.

L'invention porte sur des dérivés peptidyle sous forme d'amides, d'amides primaires ou de thioamides contenant un groupe SH ou un groupe acyle-S et possédant une fonction thérapeutique par inhibition des MMP (métalloprotéinases matricielles) et du TNF (facteur de nécrose tumorale).

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