Peptidyl prodrugs and methods of making and using the same

Details Peptidyl prodrugs and methods of making and using the same Peptidyl prodrugs and methods of making and using the same

C - Chemistry, Metallurgy

07

K

C07K 4/00 (2006.01) A61K 47/48 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07K 5/02 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2261886

Peptidyl prodrugs of therapeutic agents having an activating function are disclosed. These therapeutic agents having activating functions include those having an amino, thiol, or hydroxyl function. Methods of making and using these prodrugs are also disclosed.

L'invention concerne des promédicaments peptidyl d'agents thérapeutiques ayant une fonction d'activation. Ces agents thérapeutiques aux fonctions d'activation comprennent ceux possédant une fonction amino, thiol ou hydroxyle. Des procédés de fabrication et d'utilisation de ces promédicaments sont également décrits.

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