Peptomers with enhanced immunogenicity

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/21 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01) C07K 1/107 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2181590

The present invention releases to synthetic peptide analogues useful as therapeutic agents, immunogens or for the diagnosis of disease. In particular, it relates to peptide multimers which maintain the conformation of the native proteins from which they are derived. Peptomers constructed from peptides derived from gp120 of the human immunodeficiency virus are exemplified.

L'invention concerne des analogues de peptides synthétiques utiles en tant qu'agents thérapeutiques, immunogènes ou pour le diagnostic de maladies. Elle se rapporte, plus particulièrement, à des multimères peptidiques qui conservent la conformation des protéines natives desquelles ils sont dérivés. Des peptomères créés à partir de peptides dérivés de la protéine gp120 du virus du syndrome immunodéficitaire acquis sont également cités en exemple.

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