Percutaneously absorbable preparation, percutaneously...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 38/00 (2006.01) A61K 38/21 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/18 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61K 48/00 (2006.01) A61M 37/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2595894

It is intended to provide a transdermal absorption preparation of the self- dissolution type which is in a needle-like or thread-like shape and by which a hardly transdermally absorbable drug, etc. can be efficiently administered and so on. A transdermal absorption preparation in a needle-like or thread-like shape is prepared by using a base comprising at least one substance selected from the group consisting of proteins, polysaccharides, polyvinyl alcohol, carboxyvinyl polymers and polysodium acrylate. In this preparation, a target ingredient can be sustainedly released by forming a water-insoluble layer on the surface, holding the target ingredient in a porous substance or using a target ingredient having a long-lasting effect. It is also intended to provide a sheet holding a transdermal absorption preparation which holds the above- described transdermal absorption preparation on at least one face of a support and a transdermal absorption preparation holder whereby the above-described transdermal absorption preparation can be efficiently administered.

L'invention concerne une préparation d'absorption transdermique du type à dissolution automatique, sous forme d'aiguille ou de fil et permettant d'administrer de manière efficace un médicament faiblement absorbable à travers le derme, etc. La préparation d'absorption transdermique sous forme d'aiguille ou de fil est obtenue à l'aide d'une base comprenant au moins une substance sélectionnée parmi le groupe consistant en protéines, polysaccharides, alcool de polyvinyle, polymères de carboxyvinyle et acrylate de polysodium. Dans cette préparation, on peut libérer de façon continue un ingrédient cible en formant une couche insoluble dans l'eau à la surface, en maintenant l'ingrédient cible dans une substance poreuse ou bien en utilisant un ingrédient cible ayant un effet de longue durée. L'invention porte également sur une feuille contenant une préparation d'absorption transdermique renfermant la préparation d'absorption transdermique décrite plus haut sur au moins une face d'un support et un support de préparation d'absorption transdermique permettant l'administration efficace de la préparation d'absorption transdermique décrite ci-dessus.

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