Percutaneously absorbable preparations

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/196 (2006.01) A61K 9/06 (2006.01) A61K 9/70 (2006.01) A61K 47/04 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2379147

Percutaneously absorbable preparations (preferably nonaqueous ones, particularly matrix-type patches or ointment), containing salt-form acidic drugs and characterized by being improved in the percutaneous absorbability of the drug by the incorporation of an addition salt of a basic substance therewith and by being lowly irritant to the skin; and a percutaneous absorption accelerator for salt-form acidic drugs, containing an addition salt of a basic substance.

Cette invention concerne des préparations à absorption percutanée (de préférence des préparations non aqueuses, en particulier des timbres à matrice ou des onguents) qui renferment des médicaments acides sous forme de sels. Ces préparations se caractérisent en ce que leur absorbabilité percutanée se trouve améliorée grâce à l'adjonction d'un sel d'une substance basique et qu'elles sont peu irritantes pour la peau. L'invention concerne également un agent accélérateur d'absorption percutanée pour médicaments acides sous forme de sels auxquels on a ajouté un sel d'une substance basique.

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