Perfluoro-1-azatricyclic amine compound

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) A61K 9/00 (2006.01) A61K 31/395 (2006.01) C07D 453/02 (2006.01) C07D 487/08 (2006.01) C25B 3/08 (2006.01)

Patent

CA 1219258

ABSTRACT OF THE DISCLOSURE A novel compound of the formula, Image wherein k is zero or an integer of 1 to 2, j is an integer of from 1 or 3, ? and m are each zero or an integer of from 1 to 3, and n is an integer of from 1 to 4, the rings A, B and C being optionally substituted with at least one trifluoromethyl group or tetrafluoroethyl group is prepared by reacting the perhydro compound corresponding thereto with fluorine. The compound is useful as a material capable of carrying oxygen in an aqueous emulsion for lifsaving a patient suffering from massive hemorrhage and for preserving internal organs in transplantation.

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