C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/08 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) C07K 5/06 (2006.01) C07K 5/10 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2189526
This invention relates to compounds which are inhibitors of elastase, particularly human neutrophil elastase, and to novel processes for making the same. As inhibitors of human neutrophil elastase, the compounds are useful in the treatment of a patient afflicted with a neutrophil associated inflammatory disease.
Cette invention concerne des composés qui inhibent l'élastase, notamment l'élastase des polynucléaires neutrophiles humains, et de nouveaux procédés de production de ces inhibiteurs. Ces composés sont utiles comme inhibiteurs de l'élastase des polynucléaires neutrophiles humains dans le traitement d'un patient atteint d'une maladie inflammatoire associée aux polynucléaires neutrophiles.
Angelastro Michael R.
Burkhart Joseph P.
Curran Timothy T.
Metz William A. Jr.
Peet Norton P.
Aventisub II Inc.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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