Perfluorocarbons for use as standards in gas partial...

G - Physics – 01 – N

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150/11, 150/20,

G01N 33/84 (2006.01) A61K 9/00 (2006.01) G01N 33/96 (2006.01)

Patent

CA 1333877

A method for calibrating an instrument used to determine the po2 and PCO2 in the blood, comprising, introducing into the instrument a sample quantity of an emulsion comprising an aqueous phase, an oxygen-carrying fluorocarbon in an amount of 45% to 125% weight per volume having known stable values for PO2 and pCO2, and an effective amount of an emulsifying agent, the emulsion being biocompatible and maintaining the stable values through heat sterilization and storage for at least three months, and adjusting the calibration of the instrument to correspond to the known values of po2 and pCO2 in the emulsion.

604768

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