Perforated microparticles and methods of use

Details Perforated microparticles and methods of use Perforated microparticles and methods of use

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/12 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/72 (2006.01) A61K 45/08 (2006.01)

Patent

CA 2304819

Engineered particles are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The particles may be used in the form of dry powders or in the form of stabilized dispersions comprising a nonaqueous continuous phase. In particularly preferred embodiments the particles may be used in conjunction with an inhalation device such as a dry powder inhaler, metered dose inhaler or a nebulizer.

La présente invention concerne des particules industrielles pouvant être utilisées pour délivrer un agent bioactif dans l'appareil respiratoire d'un patient. Ces particules peuvent être utilisées sous la forme de poudres sèches ou sous la forme de dispersions stabilisées renfermant une phase continue non aqueuse. Dans des modes de réalisation préférés, les particules peuvent être utilisées conjointement avec un dispositif d'inhalation tel qu'un inhalateur à poudre sèche, un aérosol-doseur ou un nébuliseur.

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