Perfusion regulation

A - Human Necessities – 01 – N

Patent

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A01N 1/02 (2006.01)

Patent

CA 2679827

A system and method for regulating cooperatively the pressures and flows of input vessels such as both the portal vein and hepatic artery for the liver. This invention solves problems of less-than-therapeutic portal vein flow during perfusion preservation by implementing cooperative regulation between the inputs, e.g., portal vein and hepatic artery pumping systems, on an organ preservation apparatus. It includes an algorithm that adapts to the situation wherein the portal vein has reached minimum flow and maximum pressure. The cooperative regulation algorithm senses the problem with the portal vein and solves it by adjusting the hepatic artery flow conditions.

La présente invention concerne un système et un procédé permettant de réguler de manière coopérative les pressions et les flux des vaisseaux d'entrée, tels que la veine porte et l'artère hépatique pour le foie. La présente invention résout les problèmes de flux de veine porte inférieurs aux flux nécessaires pour obtenir les effets thérapeutiques désirés durant la préservation de la perfusion, grâce à la mise en AEuvre d'une régulation coopérative entre les entrées, par exemple les systèmes de pompage de la veine porte et de l'artère hépatique, sur un appareil de préservation d'organe. Celui-ci inclut un algorithme qui s'adapte à la situation lorsque la veine porte a atteint un flux minimal et une pression maximale. L'algorithme de régulation coopérative détecte le problème concernant la veine porte et le résout en ajustant les conditions de flux de l'artère hépatique.

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