Perhydroazacycloalka [1,2-a] imidazole derivatives and use...

Details Perhydroazacycloalka [1,2-a] imidazole derivatives and use... Perhydroazacycloalka [1,2-a] imidazole derivatives and use...

C - Chemistry, Metallurgy

07

D

167/208, 260/271

C07D 471/04 (2006.01) A61K 31/395 (2006.01) C07D 233/32 (2006.01) C07D 487/04 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1324378

ABSTRACT OF THE DISCLOSURE NEW PERHYDROAZACYCLOALKA[1,2-A]IMIDAZOLE DERIVATIVES AND USE THEREOF AS NOOTROPIC AGENTS Compounds of structure (1) Image (I) in which, R1 is hydrogen, C1-4alkyl, CHR6CONHR7 or CHR6COOR7 in which R6 and R7 are each hydrogen or C1-4alkyl; R2 is hydrogen, C1-5alkyl or any residue R2 of an amino acid R2CH(NH2)COOH; R3 is hydrogen, C1-4alkyl, CONH2 or CO2R8 in which R8 is hydrogen or C1-4alkyl; and n is 2, 3 or 4 processes for their preparation, intermediates useful in their preparation, pharmaceutical formulations containing them and their use in therapy as nootropic agents.

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