Perhydrothiazepine and perhydroazepine derivatives their...

C - Chemistry – Metallurgy – 07 – D

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C07D 223/12 (2006.01) C07D 281/06 (2006.01) C07D 417/00 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336774

Compounds of formula (I): Image (I) (wherein A is an alkylene group substituted by an optionally substituted amino or heterocyclic group and optionally interupted by an oxygen or sulfur atom, R2 is various organic groups, B is C1-C2 alkylene and Y is sulfur or methylene) and pharmaceutically acceptable salts and esters thereof are valuable hypotensive agents which may be prepared by a condensation reaction of the corresponding compound having an amino group in place of the group A-CH(COOH)-NH-.

533802

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