Perhydrothiazepine derivatives, their preparation and their...

Details Perhydrothiazepine derivatives, their preparation and their... Perhydrothiazepine derivatives, their preparation and their...

C - Chemistry, Metallurgy

07

D

260/238.6

C07D 281/06 (2006.01) C07D 209/48 (2006.01) C07D 307/52 (2006.01) C07D 333/18 (2006.01) C07D 333/20 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1266047

ABSTRACT OF THE DISCLOSURE Compounds of formula (I): (I) Image (wherein: R1 represents an optionally substituted alkyl, cycloalkyl, aryl, partially hydrogenated aryl or heterocyclic group; R2, R3, R4 and R5 represent hydrogen or an optionally substituted alkyl, cycloalkyl, aralkyl, aryl, heterocyclic or heterocyclic-alkyl group or any adjacent pair thereof form a cyclic structure, at least one not being hydrogen; A represents a bond, or a methylene, ethylene, oxymethyl or thiomethyl group; B represents an alkylene, alkylidene, cycloalkylene or cycloalkylidene group; and n is 0, 1 or 2) and salts and esters thereof are hypotensive agents.

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