C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/495 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/554 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2204355
Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.
On décrit des opérations de clonage et d'expression, et des vecteurs et hôtes viraux et de libération qui contiennent un acide nucléique codant au moins un peptide de canal sodium spécifique du système nerveux périphérique, un peptide isolé propre au canal sodium spécifique du système nerveux périphérique, et des composés, compositions et procédés permettant d'isoler, cristalliser, analyser aux rayons X, modéliser au niveau moléculaire, incorporer dans la conception rationnelle de médicaments, sélectionner, fabriquer et utiliser des agents thérapeutiques ou diagnostiques ou des ligands qui présentent au moins une activité de modulation concernant les canaux sodium du système nerveux périphérique.
Borden Laurence A.
Halegoua Simon
Mandel Gail
Mbm Intellectual Property Law Llp
The Research Foundation Of State University Of New York
Trophix Pharmaceuticals Inc.
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