Peripherally acting anti-pruritic opiates

Details Peripherally acting anti-pruritic opiates Peripherally acting anti-pruritic opiates

A - Human Necessities

61

K

A61K 31/451 (2006.01) A61K 31/165 (2006.01) A61K 31/17 (2006.01) A61K 31/36 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01)

Patent

CA 2346464

Anti-pruritic compositions and methods of using the compositions for the prevention or treatment of pruritus comprising formula (I) wherein M is (1), (2) or (3) wherein R, R2, R3, R4, R7, Ar1 and Ar2 are as defined in the specification in a pharmaceutically acceptable carrier.

L'invention concerne des compositions antiprurigineuses et des méthodes d'utilisation desdites compositions pour la prévention ou le traitement du prurit. Ces compositions sont représentées par la formule (I) dans laquelle M représente (1), (2) ou (3), où R, R?2¿, R?3¿, R?4¿, R?7¿, Ar?1¿ et Ar?2¿ sont tels que définis dans le descriptif. Ces compositions sont mélangées à un excipient acceptable sur le plan pharmaceutique.

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