Peripherally acting anti-pruritic opiates

Details Peripherally acting anti-pruritic opiates Peripherally acting anti-pruritic opiates

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/17 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/5377 (2006.01)

Patent

CA 2288833

Anti-pruritic compositions and methods of using the compositions for the prevention or treatment of pruritus comprising formula (I), wherein M is (a), (b) or (c), R, R2, R3, R4, R7, Ar1 and Ar2 are as defined in the specification in a pharmaceutically acceptable carrier.

Compositions anti-pruritiques et procédés d'utilisation desdites compositions pour prévenir ou traiter le prurit. Lesdites compositions sont de formule (I) dans laquelle M représente (a), (b) ou (c). Dans lesdites formules, R, R?2¿, R?3¿, R?4¿, R?7¿, Ar?1¿ et Ar?2¿ sont tels que définis dans le descriptif. Ces compositions sont mélangées à un excipient acceptable sur le plan pharmaceutique.

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