Permeant delivery system and methods for use thereof

Details Permeant delivery system and methods for use thereof Permeant delivery system and methods for use thereof

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/4468 (2006.01) A61K 31/485 (2006.01) A61K 38/16 (2006.01) A61K 38/28 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2720067

Disclosed are a patch, system, and method for delivery of a permeant composition into a subject via at least one formed pathway through a biological membrane of the subject. The patch comprises a matrix, at least one hydrophilic permeant disposed within the matrix, wherein at least a portion of the permeant can dissolve in biological moisture received from the subject, and at least one permeability enhancer disposed within the matrix. Also disclosed are systems and methods for delivery of a permeant composition into a subject via at least one formed pathway through a skin layer of the subject.

L'invention concerne un timbre, un système et un procédé pour administrer une composition de perméant à un sujet par lintermédiaire dau moins un trajet formé à travers une membrane biologique du sujet. Le timbre comporte une matrice, au moins un perméant hydrophile disposé dans la matrice, au moins une partie du perméant pouvant se dissoudre dans l'humidité biologique provenant du sujet, et au moins un simulateur de perméabilité disposé dans la matrice. Des systèmes et procédés sont également décrits pour administrer une composition de perméant à un sujet par lintermédiaire dau moins un trajet formé à travers une couche de peau du sujet.

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