Peroral active agent suspension

Details Peroral active agent suspension Peroral active agent suspension

A - Human Necessities

61

K

A61K 31/5415 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 31/10 (2006.01) A61K 31/145 (2006.01) A61K 31/18 (2006.01) A61K 31/19 (2006.01) A61K 47/02 (2006.01)

Patent

CA 2326048

The present invention relates to orally administered suspensions of pharmaceutical active substances of the NSAID type, particularly the antirheumatic agent meloxicam, which are stabilised by the addition of small amounts of highly dispersed silicon dioxide using high shear forces and adding small amounts of hydrophilic polymers to form a three-dimensional siloid structure, and a process for the preparation thereof.

L'invention concerne des suspensions à administrer par voie buccale, de principes actifs pharmaceutiques de type AINS, notamment le Meloxicam, agent antirhumatismal, qui sont stabilisées par introduction de faibles quantités de dioxyde de silicium fortement dispersé, au moyen de forces de cisaillement élevées et par adjonction de faibles quantités de polymères hydrophiles, pour former une structure siloïde tridimensionnelle. L'invention concerne en outre un procédé permettant de les utiliser.

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