C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/16 (2006.01) A61P 11/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2298866
The present invention is related to an isolated and purified polypeptide which amino acid sequence presents more than 70 % with the sequence SEQ ID NO 1. The present invention is also related to the nucleotide sequence encoding said amino acid sequence, the inhibitor directed against said sequences and their use in the diagnosis, treatment and/or prevention of lung injuries or diseases and oxidative stress-related disorders.
La présente invention concerne un polypeptide isolé et purifié dont la séquence d'acides aminés présente plus de 70 % d'homologie avec la séquence SEQ ID N0 1. La présente invention concerne également la séquence nucléotidique codant cette séquence d'acides aminés, l'inhibiteur dirigé contre ces séquences, ainsi que l'utilisation de ceux-ci dans le diagnostic, le traitement et/ou la prévention de lésions ou maladies pulmonaires et de troubles oxydatifs associés au stress.
Bernard Alfred
Falmagne Paul
Hermans Cedric
Knoops Bernard
Wattiez Ruddy
Gowling Lafleur Henderson Llp
Universite Catholique de Louvain
Universite de Mons-Hainaut
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