A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/24 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2365122
The present invention relates to the use of peroxovanadium compounds as antineoplastic agents for the treatment of cancers, particularly solid tumor malignancies. Further, this invention is directed to the use of modifications to the heteroligand structure of organified peroxovanadium compounds to modulate their activities against specific intracellular targets such as, but not limited to, the CDC 25 family of phosphatases, that may be directly involved in the pathogenesis of cancer.
La présente invention concerne l'utilisation de composés de peroxovanadium comme agents antinéoplasiques dans le traitement de cancers, en particulier des malignités de tumeurs solides. De plus, cette invention concerne l'utilisation de modifications apportées à la structure d'hétéroligand de composés de peroxovanadium organifiés pour moduler leurs activités contre des cibles intracellulaires spécifiques, telles que, de façon non exhaustive la famille CDC25 de phosphatases, pouvant être impliquées directement dans la pathogénèse du cancer.
Sandor Victor A.
Scrivens Paul James
Centre For Translational Research In Cancer
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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