Peroxynitrite decomposition catalysts and methods of use...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/22 (2006.01) A61K 33/24 (2006.01) A61K 33/26 (2006.01) A61K 33/32 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 39/00 (2006.01) C07F 9/00 (2006.01) C07F 13/00 (2006.01) C07F 15/02 (2006.01) C07F 15/04 (2006.01)

Patent

CA 2373336

This invention provides a novel class of substituted macrocyclic metallic complexes. The complexes are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, prodrug, or mixture thereof are also described.

L'invention concerne une nouvelle classe de complexes métalliques macrocycliques substitués qui sont utiles en tant catalyseurs de décomposition du peroxynitrite. Elle concerne des compositions pharmaceutiques et des méthodes de production et d'utilisation de ces composés, ou un sel, hydrate, promédicament ou mélange de ces éléments pharmaceutiquement acceptable.

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