A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/409 (2006.01) A61K 31/555 (2006.01) A61K 33/26 (2006.01) A61K 33/32 (2006.01) A61K 38/41 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 19/02 (2006.01) A61P 25/02 (2006.01) A61P 25/16 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 39/06 (2006.01)
Patent
CA 2493199
The invention relates to the use of paramagnetic 3, 8-substituted porphyrin derivatives comprising different substituents in positions 13 and 17 of the porphyrin skeleton as peroxynitrite rearrangement catalysts for the treatment and prophylaxis of diseases that are characterized by radically mediated cellular damages.
L'invention concerne l'utilisation de dérivés de porphyrine paramagnétiques substitués en 3 et en 8, avec différents substituants en positions 13 et 17 du squelette de porphyrine, comme catalyseurs de transformation du péroxynitrite pour traiter et prévenir des maladies caractérisées par une détérioration des cellules induite par des radicaux.
Depke Gisbert
Hillmann Margrit
Michl Guenter
Neuhaus Roland
Platzek Johannes
Marks & Clerk
Schering Aktiengesellschaft
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