A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12N 15/87 (2006.01) C12N 15/90 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2513226
A method of obtaining and the resulting isolated progenitor or stem cell population of proliferating cells persistently expressing a candidate molecule. Further, novel products of ex vivo gene product (e.g., protein) production and treating symptoms of neurological or neurodegenerative disorders are also provided. Fig. 15 illustrates vector used in the presently claimed invention, wherein IRES-neo sequences were cloned into the 3~ non- coding sequence (flanking exon 28) of the mouse Polr2a locus.
La présente invention concerne une technique permettant d'obtenir la population de cellules souches ou progénitrices isolées résultante de cellules proliférantes exprimant de manière persistante une molécule candidate. Cette invention concerne aussi de nouvelles techniques de production de produit génique (par exemple une protéine) ex vivo et de traitement de symptômes de troubles neurologiques ou neurodégénératifs.
Capecchi Mario R.
Rao Mahendra S.
Capecchi Mario R.
Oyen Wiggs Green & Mutala Llp
Rao Mahendra S.
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