Perturbed membrane-binding compounds

Details Perturbed membrane-binding compounds Perturbed membrane-binding compounds

A - Human Necessities

61

K

A61K 51/04 (2006.01) A61K 31/195 (2006.01) A61K 47/20 (2006.01) A61K 47/48 (2006.01) A61K 49/10 (2006.01) A61P 35/00 (2006.01) C12Q 1/04 (2006.01) C07C 311/42 (2006.01)

Patent

CA 2436601

The present invention provides uses of compounds that bind selectively to cells undergoing perturbations and alterations of their normal membrane organization, while binding to a lesser degree to cell having membranes of normal organization. These compounds are termed perturbed-membrane-binding compounds (PMBC). The PMBC group of compounds includes new compounds and also known compounds.

L'invention concerne l'utilisation de composés qui se lient sélectivement aux cellules subissant des perturbations et des modifications dans leur organisation membranaire normale tout en se liant à un plus faible degré aux cellules ayant des membranes à organisation normale. Ces composés sont désignés sous le nom de composés de liaison aux membranes perturbées (PMBC). Le groupe de composés PMBC comprend de nouveaux composés tout comme des composés déjà connus.

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