A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/10 (2006.01)
Patent
CA 2539715
The invention provides BASB232 polypeptides and polynucleotides encoding BASB232 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. The invention further provides immunogenic compositions comprising a plurality of antigens selected from at least two different categories of antigen, having different functions within Bordetella. Examples of such categories of antigen are autotransporter proteins, iron acquisition proteins, lipoproteins, adhesins and toxins/invasins.
L'invention concerne des polypeptides BASB232 et des polynucléotides codant ces polypeptides BASB232, ainsi que des procédés relatifs à leur élaboration par des techniques de recombinaison. L'invention concerne également des utilisations correspondantes, à des fins diagnostiques, prophylactiques et thérapeutiques. L'invention concerne en outre des compositions immunogènes à plusieurs antigènes appartenant au moins à deux catégories différentes d'antigènes, qui ont des fonctions différentes dans le Bordetella, par exemple : protéines autotransporteuses, protéines d'acquisition de fer, lipoprotéines, adhésines et toxines/invasines.
Castado Cindy
Denoel Philippe
Godfroid Fabrice
Poolman Jan
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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