Perylenequinone derivatives and uses thereof

Details Perylenequinone derivatives and uses thereof Perylenequinone derivatives and uses thereof

C - Chemistry, Metallurgy

07

C

C07C 50/36 (2006.01) A61K 8/35 (2006.01) A61K 31/22 (2006.01) A61K 41/00 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01) A61Q 9/00 (2006.01) C07C 50/00 (2006.01)

Patent

CA 2615510

The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.

La présente invention se rapporte à des composés qui sont des dérivés de pérylènequinone, leurs stéréoisomères et leurs atropisomères. Ces composés peuvent être particulièrement utiles en tant que photosensibilisants ou sonosensibilisants pour les thérapies par photodynamique ou sonodynamique. L'invention se rapporte aussi à divers procédés d'utilisation de ces composés pour les thérapies par photodynamique et/ou sonodynamique. Les composés sont également utiles en tant qu'agents thérapeutiques pour traiter divers troubles hyperprolifératifs.

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