Pge1-containing freeze-dried preparation and the production...

Details Pge1-containing freeze-dried preparation and the production... Pge1-containing freeze-dried preparation and the production...

A - Human Necessities

61

K

A61K 31/557 (2006.01) A61K 9/107 (2006.01) A61K 9/19 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2231682

A preparation relating to a PGE1-containing fat emulsion with excellent qualities which is superior to the conventional ones bacteriologically or in thermal or prolonged stability. The preparation is a freeze-dried one derived from a fat emulsion which contains PGE1, an oily component, an emulsifier and water and has a liquid nature (pH value) within the neutral region. In other words, it is a PGE1-containing freeze-dried preparation characterized by containing PGE1, an oily component and an emulsifier and having a liquid nature (pH value) falling within the neutral region immediately after the reconstitution (restoration) with distilled water of pH 7Ø

La présente invention concerne une préparation relative à une émulsion grasse contenant de la PGE¿1?, qui possède d'excellentes qualités et qui est supérieure aux préparations habituelles sur le plan bactériologique ainsi que pour la stabilité thermique et dans le temps. Cette préparation est lyophilisée, dérivée d'une émulsion grasse qui contient de la PGE¿1?, un constituant huileux, un émulsifiant et de l'eau et qui, à l'état liquide, est chimiquement neutre (pH). En d'autres termes, il s'agit d'une préparation lyophilisée contenant de la PGE¿1?, caractérisée en ce qu'elle contient de la PGE¿1?, un constituant huileux et un émulsifiant et dont le pH à l'état liquide est dans le domaine neutre immédiatement après la reconstitution avec de l'eau distillée ayant un pH de 7,0.

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